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Year : 2022  |  Volume : 2  |  Issue : 3  |  Page : 842

Microsporidial Keratitis

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Date of Web Publication16-Jul-2022

Correspondence Address:
Prof. Arun Kumar Jain
Professor of Ophthalmology, Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh – 160 012
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_139_22

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How to cite this article:
Thakur A, Sharma SP, Gupta B, Limbu S, Malhotra C, Jain AK. Microsporidial Keratitis. Indian J Ophthalmol Case Rep 2022;2:842

How to cite this URL:
Thakur A, Sharma SP, Gupta B, Limbu S, Malhotra C, Jain AK. Microsporidial Keratitis. Indian J Ophthalmol Case Rep [serial online] 2022 [cited 2022 Oct 6];2:842. Available from: https://www.ijoreports.in/text.asp?2022/2/3/842/351122

A 40-year-old female presented with pain, redness, watering, and foreign body sensation for three days duration. Visual acuity was 20/120 with diffuse conjunctival congestion and multifocal fine-to-coarse, stuck-on epithelial lesions [Figure 1]a. Careful corneal scrapping on KOH mount revealed a “Microsporidial Bowl” with central microsporidial spores (black arrow) surrounded by epithelial cells [Figure 1]b. These lesions fluoresced bluish-white on combined KOH and Calcofluor stain [Figure 1]c. Classical clinical picture, easy diagnosis with Calcofluor staining and timely treatment with topical moxifloxacin with voriconazole led to complete resolution of lesions in 14 days with restoration of visual acuity to 20/20.[1],[2]
Figure 1: (a) Slit lamp examination of the right eye revealed diffuse conjunctival congestion with multifocal fine to coarse stuck on epithelial lesions on the cornea. (b) KOH mount from the corneal scraping revealed a “Microsporidial Bowl” with central microsporidial spores surrounded by epithelial cells. (c) Fluorescent microscope using ultraviolet light highlights oval, non-budding bluish white microsporidial spores on combined KOH and Calcofluor staining

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Loh RS, Chan CM, Ti SE, Lim L, Chan KS, Tan DT. Emerging prevalence of microsporidial keratitis in Singapore: Epidemiology, clinical features, and management. Ophthalmology 2009;116:2348–53.  Back to cited text no. 1
Moshirfar M, Somani SN, Shmunes KM, Espandar L, Gokhale NS, Ronquillo YC, et al. A narrative review of microsporidial infections of the cornea. Ophthalmol Ther 2020;9:265-78.  Back to cited text no. 2


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